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Pycnogenol is the registered trademark name for a French formula. According to researchers, it may help prevent the rise in free radicals typically seen after exercise, which could cause muscle fatigue and damage [9]. Regardless, a natural option is available and far worth the wait. Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [23]. Procyanidins are chain-like structures consisted of catechins similar to some found in green tea (the green tea catechins that do not have 'gallate' in their names). Here are the many health benefits believed to be possible with Pycnogenol: Reduces "leaky" blood vessels by making the wall proteins (collagen, elastin) more resistant to damage. First and foremost, start eating an anti-inflammatory Local Raw Honey (Bee Pollen) Considering how good it tastes, having some raw honey Apple Cider Vinegar (ACV) You can now find high-quality apple cider vinegar in . Improve cardiovascular health. Clinical research suggests that Pycnogenol is possibly effective for improving athletic performance. Speak with your doctor before supplementing. In a clinical trial of 116 women, Pycnogenol (60 mg/day) reduced menstrual pain and the need for additional painkillers, taken over 2 cycles. Mental function. 7. If you are taking blood thinners, do not take pine bark extract or Pycnogenol unless approved by your doctor. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. It seems to lower blood pressure and improve blood flow to the legs. More specifically, because it strengthens the capillaries in the retina, Mirtogenol can help prevent retinopathy. Neuroprotective effect of Pycnogenol® following traumatic brain injury. In 22 German heavy smokers, platelet aggregation was prevented by 500 mg of aspirin or 100 mg Pycnogenol. After taking a break for one to two weeks, they can start taking it again for several weeks. Researchers suggest that it may have stronger benefits than elastic compression stockings. New research has shown promising results for those dealing with erectile dysfunction (ED) and diabetes. Consequently, blood pressure is lowered. Ac., CYT, 12 Benefits of Ginkgo Biloba (Plus Side Effects & Dosage), Tongkat Ali (Eurycoma longifolia): Everything You Need to Know, reduce blood sugar levels in people with diabetes, are within two weeks of a scheduled surgery, medications, herbs, and supplements that affect the blood or clotting. There is limited evidence that it could be used in treating Attention Deficit Hyperactivity Disorder (ADHD). This review noted that pine bark extract may also help with: In addition to its skin-healing properties, pine bark extract also shows promise for helping children manage ADHD symptoms. No side effects were noted, unlike its synthetic counterpart. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. Your email address will not be published. Another study in 2012 showed that Pycnogenol alone, at a dose of 75 mg/day, increased skin hydration by 8% after just 6 weeks; in women with dry skin at baseline the increase was 21%. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. In another trial, a combination supplement (Pycnogenol 60 mg/day, L-arginine 690 mg/day and aspartic acid 552 mg/day) improved erectile dysfunction and sexual satisfaction in men after 8 weeks. Pycnogenol (200 mg/day) may reduce muscle cramps and pain according to a study of 66 healthy people, athletes, and those with venous problems after 4 weeks. Eye health. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. While the aspirin reduced the risk for cardiovascular disease and colorectal cancer, among other cancers, the risk of gastrointestinal bleeding outweighed those benefits, creating more risks to the body. Four hundred years later, a French researcher named Jacques Masquelier did some studies to understand why this natural remedy was so effective. The following purported benefits of Pycnogenol are only supported by limited, low-quality clinical studies. Pycnogenol significantly improved the heavy feeling as well as the swelling. It had the best results when combined with compression stockings, but worked just as well alone [28]. Some of the top lutein-rich foods to include in your diet are dark leafy greens like spinach and kale, broccoli . Forty patients were treated with either 600 mg chestnut seed extract a day or 360 mg Pycnogenol a day over a period of four weeks. Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. A total of 40 patients with retinopathy (damage to the retina part of the eye) from diabetes and other vascular causes were enrolled in one study. A combination supplement (pycnogenol with collagen, coenzyme Q10, and other ingredients) reduced skin aging, elasticity, hydration, and tonicity in a study of 30 women [65]. Pycnogenol has been well-tolerated in most studies performed thus far. Although these may still be high quality, the active compounds are more likely to vary. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects [84]. Fundukian, L.J. Additionally, the results showed that the extract has significant anti-pseudomonas activity, making it a potential natural remedy and possible preventive measure for infections. The combination of Panax ginseng and vitamin E also appears to have an effect. Pycnogenol has given indications that it might be able to benefit heart and artery health, to include reducing high blood pressure. Higher doses (200 mg/day) may improve blood vessel health and function after 8 weeks according to a study of 23 people with heart disease [38]. This ensures that there is a healthy flow of blood to and from the heart. The dosage in most clinical studies varied between 50-360 mg/day. In addition to general healthy eating, some specific vitamins and minerals may help improve ADHD. In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74]. In the study, women taking Pycnogenol were more satisfied and compliant to the regimen [24]. All rights reserved. He later extracted proanthocyanidins from the European coastal pine tree, which he named Pycnogenol.. If you take any medications regularly, talk to your doctor before you start using pycnogenol supplements. Although the preliminary studies show many health benefits with the use of Pycnogenol, future larger and better studies are needed. ", Panminerva Medica: "Supplementation with Pycnogenol improves signs and symptoms of menopausal transition.". Pycnogenol pine bark extracts contain a unique blend of flavonoids whose antioxidant action is over is 50 times more powerful than vitamin E, 20 times more powerful than vitamin C and 16 times more active than grapeseed extracts. Instead, use plain water to wipe yourself and then dry your bottom afterward. This article explains which supplements are believed to be safe during pregnancy and which ones you should avoid. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. 40 years of research has been dedicated to establishing the safety of Pycnogenol and its benefits for human health. Lets begin with asthma. Still, more research is needed to better understand these findings and pine bark extracts role in reducing damage from head trauma. It is chronic venous insufficiency, a common disease among people who are obese or elderly and those who lead a sedentary lifestyle. Some health benefits of Pycnogenol include:. There were 88 in the control group and 81 in the Pycnogenol group. Pycnogenol is a compound of natural chemicals. Importantly, all studies found that Pycnogenol has to be taken at least 5 weeks before the allergy season in order to see potential benefits, with the best results in those who take it 7-8 weeks ahead. Children who took a pine bark extract supplement for one month had healthy antioxidant levels. A review was conducted of French maritimepine bark extract, specifically using the nutritional supplement Pycnogenol. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. In the placebo group, the retinopathy worsened; whereas, in the Pycnogenol-treated group, there was no deterioration. Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. In the study, the placebo group had higher IgE antibodies to the birch allergen than those who took Pycnogenol during the allergy season [17]. Pycnogenol effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women [Abstract]. Diarrhea. The study suggests it may increase desire, arousal, lubrication, orgasm, satisfaction and reduce pain [70]. Some people who have asthma have higher levels of leukotrienes in their blood. For most people, pine bark extract doesn't cause any side effects. Can Pycnogenol help? Pycnogenol is thought to be an antioxidant that helps protect cells from damage. In 1535, a French explorer by the name of Jacques Cartier found himself ice-bound on the St. Lawrence River. 3. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. Another highlight of grapes nutrition is the presence of polyphenols, which have been shown to decrease chronic inflammation. However, it's always a good idea to start with a low dose so you can monitor how your body responds. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. There is insufficient evidence to support the use of Pycnogenol for any of the uses listed below. Prenatal nutrition can be confusing. Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). (2006). A study of 147 people found that pycnogenol (100 mg/day) may improve running, push-ups, and sit-ups endurance in recreational athletes over an 8-week training program. A 2021 review in the Arab Journal of Urology listed it first among "promising herbal remedies" for ED. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". Pycnogenol (125 mg/day) had the same effects in another study of 48 people with diabetes and high blood pressure. Here are some basic guidelines as reported by WebMD: While most studies do not indicate major side effects, pine bark extract may cause irritability and fatigue, and could interact with other drugs. Dr. Eric L. Zielinski is a sought-after natural . Some risks associated with Pycnogenol include:, Pycnogenol and other maritime tree barks have not been studied as extensively as traditional medicine. Regardless of what youre using it for, its best to start with the lowest possible dose. Read More: Health Benefits of Peanut Butter. Pycnogenol may stimulate the immune system. Set Ascending Direction. That way, your doctor can check on any potential side effects or interactions with medications. is a clickable link to peer-reviewed scientific studies. Pycnogenol lowered leukotrienes as well. Pycnogenol has not been found to cause these issues however, it may take a little longer the feel the relief from pain than aspirin. They were given Pycnogenolfor a period of 10 days. Too much pressure signals that your heart might be working too hard. blood in the urine. Prunes and prune juice have many health benefits. Some pycnogenol supplements are mixed with other antioxidants, such as vitamin C. Pine bark extracts other than pycnogenol are also sold. They also had normalized fasting glucose levels and blood pressure, which can also reduce a persons risk of heart problems. According to a meta-analysis of 9 trials including 549 people, 150-200 mg/day for at least 12 weeks may reduce both diastolic and systolic blood pressure [36]. Pine bark extract contains active ingredients that can also be found in peanut skin, grape seed, and witch hazel bark. The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. Our website services, content, and products are for informational purposes only. But two months ago, erectile dysfunction health food with the help of the Divine Tool Alliance, the price of all materials related to the puppet mechanism was raised by 20 erectile dysfunction health food 30 , and the price of selling the puppet was reduced by 10. Erythritol: Is This Healthy Sweetener the Real Deal? In long-haul flights, Pycnogenol could be an effective prevention for blood clots. Its used as a natural supplement for several conditions, including dry skin and ADHD. In combination with Mirtoselect, Pycnogenol may improve blood flow to the eye and reduce eye blood pressure as shown in a trial of 38 people [81]. 1. Last medically reviewed on January 24, 2018. Pine bark extract can make a great addition to your nutritional arsenal for its potent antioxidant support, as well as its added support for blood flow, blood sugar, inflammation, immunity, brain function and skin support. Plus, it reduced total and LDL (bad) cholesterol. There is a seemingly growing problem with skin exposure to ultraviolet radiation and the confusion of how to get vitamin D from the sun while avoiding these skin-damaging rays. Pycnogenol (100 mg/day) improved menopausal symptoms and quality of life in a clinical trial of 35 women after 8 weeks [68]. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. Discover what the research says about elimination diets, foods to eat, and more. Pycnogenol supplementation reduced skin redness from UV rays in a trial of 21 people over 8 weeks. It can also be used for local application on the skin without the risk of side effects. In oneparticular study published in Research in Pharmaceutical Sciences, researchers investigated the antibacterial activity of pine bark extract essential oil on staph infections, E. coli and pseudomonas infections. Therefore, those who have autoimmune conditions could see their symptoms increase after taking it., Since Pycnogenol is used for so many conditions, doses can vary. Its quality is specified in the United States Pharmacopeia [3]. 4. Start with a low dose so you can be sure it doesnt cause any side effects. Pycnogenol (up to 200 mg/day) may improve asthma and reduce inflammatory asthma markers in the blood, leukotrienes, after 4 weeks, according to a randomized placebo-controlled trial of 26 asthma patients [14]. Vertigo. It may cause side effects such as: Dizziness. Researchers suggest this benefit may be due to an increase in glutathione and SOD, two antioxidants that may reduce inflammation and oxidative stress in Crohns [76]. It also may help those on blood pressure medications to reduce their dose [32]. (2013). Side effects. Pycnogenol is known under different names in some countries, such as Oligopin, and Flavangenol in Japan [4, 5]. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. This supplement possibly activates the immune system. $31.99. One study of 211 found that Pycnogenol may help prevent edema and ankle swelling from long flights [27]. Pycnogenol (150 mg/day) reduced LDL and increased HDL cholesterol in a trial of 25 healthy people after 6 weeks [55]. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. All rights reserved. In the following sections, well discuss the common forms and dosages of Pycnogenol that are commercially available. A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. Quality and active ingredients in supplements may vary widely from maker to maker. A high number signals high blood pressure. A new peer-reviewed study, published in the Bratislava Medical Journal, shows that daily supplementation with the natural antioxidant, Pycnogenol, a French maritime pine bark extract, can improve the symptoms of ED.. , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. $47.99. DOI: Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 50 to 450 milligrams of pine bark extract daily, Supplements During Pregnancy: Whats Safe and Whats Not, The ADHD Diet: What Works and What Does Not, Berberine A Powerful Supplement With Many Benefits, The Top Health Benefits of Prunes and Prune Juice, What to Know About Andrographis Supplements: Potential Benefits and Uses, Kerry Boyle D.Ac., M.S., L.Ac., Dipl. Researchers suggest that it may epigenetically turn off genes responsible for joint damage (ADAMTS) as well as reduce inflammation enzymes (MMP3) and cytokines (IL 1-beta) [47, 48]. It also slightly decreased blood pressure and increased testosterone [67]. It also seems to help with cell regeneration and replication. It can also stabilize mast cells, which release histamine and trigger allergic reactions. Research indicates that Pycnogenol provides an increase in survival performance of train athletes. 2. . If you are thinking of taking Pycnogenol for a serious health condition like asthma or high blood pressure, check with your doctor., People who have autoimmune conditions like multiple sclerosis or lupus should talk to their doctor before trying Pycnogenol. SelfDecode does not treat, diagnose or cure any conditions, In a study of 77 people with symptoms of Irritable Bowel Syndrome (IBS), Pycnogenol (150 mg/day) improved symptoms and reduced the frequency of attacks [77]. Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for .
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